top of page
hero section background in light-purple tone with a hyper-realistic infusoria, almost like

Microbiome intelligence for health innovations across industries

Use cases

pharmacology pills .jpg

Pharma & Biotech – Target discovery, preclinical modeling, patient stratification, responder analysis, and post-market insights.

people in hospital seeking help.jpg

Precision Health & Providers – Clinical decision support and differential diagnosis.

food and nutrition probiotics production

Food & Nutrition – Ingredient R&D, product development, and diet-linked health monitoring.

cosmetics creme science production .png

Cosmetics & Personal Care – Skin product innovation and post-market safety monitoring.

agriculture soil scientist .jpg

Agriculture – Crop health, soil microbiome optimization, and sustainable farming solutions

Researcher

Our long-term vision is to enable multiple industries with microbiome-driven insights, while our immediate focus is on the most urgent challenge – redefining drug development for safer, more effective therapies

The Clinical Trial Problem: Broken and Inefficient

  • Phase I–III attrition: ~90% of drugs fail before approval

  • Each trial costs $50–100M+ and runs 5–7 years

  • Even “successful” drugs help only ~40% of patients

  • Non-responder recruitment = delays, wasted budgets, failed approvals

  • Microbiome impact on response is ignored in almost all trials

Response Prediction and Stratification Tool Demo

Microbiome index 

Proprietary pipeline that profiles the microbiome down to the strain level across bacteria, fungi, viruses, and phages in a single run. Each finding is enriched with a knowledge graph that links microbes and genes to biochemical pathways, drug interactions, and clinical relevance.

We recreate in ex-vivo how diverse compounds behave within real, living microbiome systems.

The methodology allows to discover and describe

  • Strain-level shifts

  • Functional pathway changes

  • Compound metabolism

  • Response markers

  • Metabolite profiles

Drug-Microbiome Modeling

Synapticore ML

A machine learning model purpose-built for multi-omic microbiome data. SynaptiCore ingests  microbial profiles, clinical variables, genomic and drug data, and converts them into unified feature representations. This allows the model to learn non-linear relationships between microbial composition, host physiology, and therapeutic outcomes.

Our 
Mission

Raise drug efficacy rates from 40% to
60–80%

Cut drug trial timelines by the factor of
2x

Be the foundational technology for microbiome-based clinical development
globally

Our Team

Fedor Lipskerov

Biochemistry Scientist | Molecular Biology | Technology

Yulia Gulyanskaya

Business Development | Former Director of Global Strategy and Business Development, IBM Watson Health

Shaul Sapielkin

ML | Bioinformatics

Boris Polyak

Cloud computing AWS | AI

Our Advisors

Dr. Milena Pitashny

Dr. Milena Pitashny

Director of the Clinical Microbiology Laboratory | Hillel Yaffe Medical Center

Prof. Naama Geva-Zatorsky

Prof. Naama Geva-Zatorsky

Principal Investigator | Gut Microbiota – Host Interactions | Technion - Israel Institute of Technology

synaptiflora

Microbiome intelligence for health innovations across industries

Israel, Haifa

bottom of page